Positive and negative selection on the mitochondrial genome.

نویسندگان

  • Colin D Meiklejohn
  • Kristi L Montooth
  • David M Rand
چکیده

Several recent studies have confirmed that mitochondrial DNA variation and evolution are not consistent with the neutral theory of molecular evolution and might be inappropriate for estimating effective population sizes. Evidence for the action of both positive and negative selection on mitochondrial genes has been put forward, and the complex genetics of mitochondrial DNA adds to the challenge of resolving this debate. The solution could lie in distinguishing genetic drift from 'genetic draft' and in dissecting the physiology of mitochondrial fitness.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Rates and relations of mitochondrial genome evolution across the Echinoidea, with special focus on the superfamily Odontophora

In order to better characterize the placement of genus Tripneustes, as a representative of the Toxopneustidae family within the broader sea urchin mitochondrial (MT) phylogeny, the complete MT genome of Tripneustes gratilla was generated and compared with all published echinoid MT genomes currently available on NCBI GenBank. The MT genome phylogeny supports the existence of the superfamily Odon...

متن کامل

Comparison of Phylogenetic and Evolutionary of Nucleotide Squences of HVR1 region of Mitochondria genom in Goats and Other Livestock Species

     Maintaining genomic diversity in goat populations in different parts of Iran is essential for breeding programs, increasing production, survival, resistance to diseases, and various environmental changing conditions. The aim of the present study was to determine the sequence of HVR1 from the mitochondrial genome of Iranian native goats including Sistani, Pakistani, Black and Lorry ecotypes...

متن کامل

Appraisal of the entire mitochondrial genome for DNA barcoding in birds

DNA barcoding based on a standardized region of 648 base pairs of mitochondrial DNAsequences from Cytochrome C Oxidase 1 (COX1) is proposed for animal species identification.Recent studies suggested that DNA barcoding has been effective for identifying 94% of birdspecies. The proposed threshold of 10 times the average intraspecific variation could be used forthe identification and delimitation ...

متن کامل

Sequencing and Molecular Analysis of ATP 6 and ATP 8 of Mitochondrial Genome in Khorasanian Native Chickens

In order to perform breeding programs and improve production of native chickens, preserving genetic diversity in different areas of Iran is important due to the reduced available population. Genome sequencing is considered the most functional approach to determine the phylogeny relation between close populations. The aim of the present study was the evaluation of the phylogeny and genetic nucle...

متن کامل

کاوش ژنومی برای ردیابی نشانه‌های انتخاب در اسب نژاد ترکمن

Abstract Selection not only increases the frequency of new-useful mutations but also remains some signals throughout the genome. Since these areas are often control economically important traits, identifying and tracking these areas is the most important issue in the animal genetics. The aim of this study was to detecting signals of selection in the genome of Turkmen horse using 70K SNP chip...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Trends in genetics : TIG

دوره 23 6  شماره 

صفحات  -

تاریخ انتشار 2007